KE505: Organic chemistry

Study Board of Science

Teaching language: Danish or English depending on the teacher
EKA: N530021112, N530021122, N530021102
Assessment: Second examiner: None, Second examiner: External
Grading: Pass/Fail, 7-point grading scale
Offered in: Odense
Offered in: Spring
Level: Bachelor

STADS ID (UVA): N530021101
ECTS value: 10

Date of Approval: 31-10-2022


Duration: 1 semester

Version: Approved - active

Comment

None

Entry requirements

None

Academic preconditions

Students taking the course are expected to:

  • have knowledge of basic general and organic chemistry, including especially the structure and functional groups of organic molecules as well as the concept of pH and introductory thermodynamics.
  • have knowledge of the importance of organic molecules in biochemistry, including biological macromolecules.
  • have knowledge of simple inorganic molecules and salts and their properties.
  • have practical experience with laboratory work and general laboratory safety.

Course introduction

The aim of the course is to provide a detailed and systematic review of organic chemistry. The course thus forms a basis of advanced chemistry and pharmacy courses as well as a bachelor project in organic chemistry and medicinal chemistry.

The course primarily builds on the competencies acquired in the first-year course KE501 or equivalent with a fundamental content of general and organic chemistry. The course is based on the students being in the first or second year of a study program in chemistry, pharmacy or chemical engineering, so that they can relate the course to other subject disciplines within chemistry, e.g. biochemistry, spectroscopy, technical chemistry, physical chemistry or inorganic chemistry.

In relation to the competence profile of the degree it is the explicit focus of the course to: (1) form a solid theoretical basis in organic chemistry with a view to being able to plan the synthesis of chemical substances for use in e.g. materials, pharmaceuticals, catalysts etc., as well as (2) form the experimental basis for the practical performance of chemical synthesis, including handling the safety aspects in an organic synthesis laboratory.

With this, the course forms the background to e.g. pharmacy students' further studies within medicinal chemistry and drug development, chemistry students' further studies within organic synthesis, materials chemistry and nanotechnology, and chemical engineering students' further studies in process engineering.

Expected learning outcome

The learning objective of the course is that the student demonstrates the ability to:

  • describe the structure of complicated organic molecules; i.e. to be able to identify and name the constituent functional groups and structural elements, as well as to describe the stereochemical properties
  • use knowledge of organic reactions and reagents to write up and plan syntheses in one or more steps and be able to argue for the formation of by-products
  • write up and use reaction mechanisms
  • explain and analyze the stereochemical consequences of various reactions
  • perform selected unit operations in an organic synthesis laboratory
  • produce selected organic compounds according to regulations

Content

The following main topics are contained in the course:

  • Stereochemistry
  • Alkanes and their reactions
  • Alkenes and their reactions
  • Alkynes and their reactions
  • Delocalization and resonance
  • Diener's reactions
  • Substitution reactions
  • Elimination reactions
  • Reactions of alcohols, amines, ethers and epoxides
  • Aromaticity and reactions of benzene
  • Reactions of substituted benzenes
  • Reactions of carbonyl compounds
  • Oxidation/reduction reactions
  • Heterocyclic compounds as well as simple biomolecules.
  • Correct behavior in terms of safety in an organic synthesis laboratory
  • Common unit operations in an organic synthesis laboratory

Literature

P. Y. Bruice: Organic Chemistry, 8th Ed.
See itslearning for syllabus lists and additional literature references.

Examination regulations

Prerequisites for participating in the exam a)

Timing

Spring

Tests

Participation in laboratory exercises

EKA

N530021112

Assessment

Second examiner: None

Grading

Pass/Fail

Identification

Full name and SDU username

Language

Normally, the same as teaching language

Examination aids

See danish version

ECTS value

0

Additional information

The prerequisite examination is a prerequisite for participation in exam element b)

Exam element b)

Timing

Spring

Prerequisites

Type Prerequisite name Prerequisite course
Examination part Prerequisites for participating in the exam a) N530021101, KE505: Organic chemistry

Tests

Reports based on laboratory exercises

EKA

N530021122

Assessment

Second examiner: None

Grading

Pass/Fail

Identification

Full name and SDU username

Language

Normally, the same as teaching language

Examination aids

To be announced during the course 

ECTS value

2

Exam element a)

Timing

June

Tests

Written exam

EKA

N530021102

Assessment

Second examiner: External

Grading

7-point grading scale

Identification

Student Identification Card

Language

Normally, the same as teaching language

Duration

5 hours

Examination aids

All common aids are allowed e.g. books, notes, computer programmes which do not use internet etc. 

Internet is not allowed during the exam. However, you may visit the course site in itslearning to open system "DE-Digital Exam". If you wish to use course materials from itslearning, you must download the materials to your computer the day before the exam. During the exam you cannot be sure that all course materials is accessible in itslearning.   

ECTS value

8

Indicative number of lessons

104 hours per semester

Teaching Method

At the faculty of science, teaching is organized after the three-phase model, ie. intro, training and study phase.

The teaching activities are implemented as an estimated suggested allocation of the workload of an average student as follows:

  • Intro phase (lectures): 36 hours
  • Training phase: 68 hours, of which 34 hours of tutorials and 26 hours of laboratory

The intro phase consists of lectures, where dialogue is primarily created using a clicker system. A brief introduction to the course's topics and the way to acquire competencies is given here as a supplement to the textbook, which the students are expected to study independently.

In the training phase, competencies are cultivated within the central parts of the course - not least writing up mechanisms as the basis of organic reactions. The tutorials are based on group work around problem solving, and differentiated teaching is practiced to some extent. In the laboratory exercises, the students work independently with practical exercises in chemical synthesis.

In the study phase, the students are expected to work with self-study of the textbook and problems included here. In addition, both written homework and laboratory reports are included as central elements in the study phase, and the students can expect feedback from a teacher on both parts. The students are also expected to spend part of the study phase catching up on the training phase problems as well as reserving a smaller part for repetition leading up to the written exam.

It is expected that the workload is evenly spread throughout the semester.

Teacher responsible

Name E-mail Department
Jan Oskar Jeppesen joj@sdu.dk Institut for Fysik, Kemi og Farmaci

Timetable

Administrative Unit

Fysik, kemi og Farmaci

Team at Educational Law & Registration

NAT

Offered in

Odense

Recommended course of study

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BSc Major in Chemistry - registration 1 September 2020 | Odense 2 E22
BSc Major in Chemistry - registration 1 September 2020 | Odense 2 E22
BSc Major in Chemistry - registration 1 September 2020 | Odense 2 E23
BSc Major in Chemistry - registration 1 September 2021 | Odense 2 E22
BSc Major in Chemistry - registration 1 September 2021 | Odense 2 E23
BSc Major in Chemistry - registration 1 September 2021 | Odense 2 E23
BSc Major in Chemistry - registration 1 September 2021 | Odense 2 E22
BSc Major in Chemistry - registration 1 September 2022 | Odense 2 E22
BSc Major in Chemistry - registration 1 September 2022 | Odense 2 E22
BSc Major in Chemistry - registration 1 September 2022 and 2023 | Odense 2 E23
BSc Major in Chemistry and minor in Computer Science - registration 1 September 2020 | Odense 2 E23
BSc Major in Chemistry and minor in Computer Science - registration 1 September 2020 | Odense 2 E22
BSc Major in Chemistry and minor in Computer Science - registration 1 September 2021 | Odense 2 E22
BSc Major in Chemistry and minor in Computer Science - registration 1 September 2021 | Odense 2 E23
BSc Major in Chemistry and minor in the subject area of Natural Science - registration 1 September 2020 | Odense 2 E22
BSc Major in Chemistry and minor in the subject area of Natural Science - registration 1 September 2020 | Odense 2 E23
BSc Major in Chemistry and minor in the subject area of Natural Science - registration 1 September 2020 | Odense 2 E23
BSc Major in Chemistry and minor in the subject area of Natural Science - registration 1 September 2020 | Odense 2 E22
BSc Major in Chemistry and minor in the subject area of Natural Science - registration 1 September 2021 | Odense 2 E22
BSc Major in Chemistry and minor in the subject area of Natural Science - registration 1 September 2021 | Odense 2 E23
BSc Major in Chemistry and minor in the subject area of Natural Science - registration 1 September 2022 | Odense 2 E22
BSc Major in Chemistry and minor in the subject area of Natural Science - registration 1 September 2022 | Odense 2 E22
BSc Major in Chemistry and minor in the subject area of Natural Science - registration 1 September 2022 and 2023 | Odense 2 E23
BSc Major in Chemistry and minor in the subject area of Natural Science - registration 1 September 2022 and 2023 | Odense 2 E23
BSc Major in Chemistry with specialization in Medicinal Chemistry - registration 1 September 2022 and 2023 | Odense 2 E23
BSc Biochemistry and molecular biology with special minor in Chemistry 40 ECTS - Registration 1 September 2019 | Odense 4 E22
BSc Biochemistry and molecular biology with special minor in Chemistry 40 ECTS - Registration 1 September 2020 | Odense 4 E23
BSc Biochemistry and molecular biology with special minor in Chemistry 40 ECTS - Registration 1 September 2020 | Odense 4 E22
BSc Biochemistry and molecular biology with special minor in Chemistry 40 ECTS - Registration 1 September 2021 | Odense 4 E23
BSc Biochemistry and molecular biology with special minor in Chemistry 40 ECTS - Registration 1 September 2021 | Odense 4 E22
BSc Major in Chemistry - registration 1 September 2019 | Odense 4 E22
BSc Major in Chemistry - registration 1 September 2019 | Odense 4 E22
BSc Major in Chemistry and minor in the subject area of Natural Science - registration 1 September 2019 | Odense 4 E22
BSc major in Pharmacy - Registration 1 September 2019 Bachelor of Science (BSc) in Pharmacy | Odense 4 E22
BSc major in Pharmacy - Registration 1 September 2020, 2021 and 2022 Bachelor of Science (BSc) in Pharmacy | Odense 4 E22
BSc major in Pharmacy - Registration 1 September 2020, 2021, 2022 and 2023 Bachelor of Science (BSc) in Pharmacy | Odense 4 E23
No longer applicable (31 August 2020): BSc Biochemistry and molecular biology with special minor in Chemistry 40 ECTS - Registration 1 September 2019 | Odense 4 E22
No longer applicable (31 August 2020): BSc major in Pharmacy - Registration 1 September 2019 Bachelor of Science (BSc) in Pharmacy | Odense 4 E22
BSc Minor in Chemistry for major in Biology - registration 1 September 2019 | Odense 6 E22
BSc Minor in Chemistry for major in Biology - registration 1 September 2019 and 2020 | Odense 6 E22
BSc Minor in Chemistry for major in Biology - registration 1 September 2020 | Odense 6 E23
BSc Minor in Chemistry for major in Biology - registration 1 September 2020, 2021 and 2022 | Odense 6 E22
BSc Minor in Chemistry for major in Biology - registration 1 September 2020, 2021, 2022 and 2023 | Odense 6 E23
BSc Minor in Chemistry for major in Mathematics and Computer Science - registration 1 September 2018, 2019 and 2020 | Odense 6 E22
BSc Minor in Chemistry for major in Mathematics and Computer Science - registration 1 September 2019, 2020, 2021 og 2022 | Odense 6 E22
BSc Minor in Chemistry for major in Mathematics and Computer Science - registration 1 September 2020 | Odense 6 E23
BSc Minor in Chemistry for major in Mathematics and Computer Science - registration 1 September 2020, 2021, 2022 and 2023 | Odense 6 E23
BSc Minor in Chemistry for major in Physics - registration 1 September 2019 and 2020 | Odense 6 E22
BSc Minor in Chemistry for major in Physics - registration 1 September 2019, 2020, 2021 and 2022 | Odense 6 E22
BSc Minor in Chemistry for major in Physics - registration 1 September 2020 | Odense 6 E23
BSc Minor in Chemistry for major in Physics - registration 1 September 2020, 2021, 2022 and 2023 | Odense 6 E23
BSc Minor in Chemistry for major in Sports and Health - registration 1 September 2019 | Odense 6 E22
BSc Minor in Chemistry for major in Sports and Health - registration 1 September 2020 | Odense 6 E22
BSc Minor in Chemistry for major in Sports and Health - registration 1 September 2020 | Odense 6 E23
BSc Minor in Chemistry for major in Sports and Health - registration 1 September 2021 | Odense 6 E23
BSc Minor in Chemistry for major in Sports and Health - registration 1 September 2021 | Odense 6 E22
BSc Minor in Chemistry for major in Sports and Health - registration 1 September 2022 | Odense 6 E22
BSc Minor in Chemistry for major in Sports and Health - registration 1 September 2022 and 2023 | Odense 6 E23
BSc Minor in Chemistry for major in subject area outside Natural Sciences - registration 1 September 2019 | Odense 6 E22
BSc Minor in Chemistry for major in subject area outside Natural Sciences - registration 1 September 2020 | Odense 6 E23
BSc Minor in Chemistry for major in subject area outside Natural Sciences - registration 1 September 2020 | Odense 6 E22
BSc Minor in Chemistry for major in subject area outside Natural Sciences - registration 1 September 2021 | Odense 6 E23
BSc Minor in Chemistry for major in subject area outside Natural Sciences - registration 1 September 2021 | Odense 6 E22
BSc Minor in Chemistry for major in subject area outside Natural Sciences - registration 1 September 2022 | Odense 6 E22
BSc Minor in Chemistry for major in subject area outside Natural Sciences - registration 1 September 2022 and 2023 | Odense 6 E23
No longer applicable (31 August 2020): BSc Minor in Chemistry for major in Biology - registration 1 September 2019 | Odense 6 E22
No longer applicable (31 August 2020): BSc Minor in Chemistry for major in Mathematics and Computer Science- registration 1 September 2019 | Odense 6 E22
No longer applicable (31 August 2020):BSc Minor in Chemistry for major in Physics - registration 1 September 2019 | Odense 6 E22
No longer applicable BSc Minor in Chemistry for major in Biology - registration 1 September 2019, 2020 og 2021 | Odense 6 E22
No longer applicable BSc Minor in Chemistry for major in Biology - registration 1 September 2020 og 2021 | Odense 6 E23

Transition rules

Transitional arrangements describe how a course replaces another course when changes are made to the course of study. 
If a transitional arrangement has been made for a course, it will be stated in the list. 
See transitional arrangements for all courses at the Faculty of Science.